Push processing formulas

The ESI MS method yielded results to identify isothiazolium salts 62 and 63 (05SUC211). The aqueous methanolic solution of the salts gave by application of this spray method intensive signals of the cation (ESI pos.) and accordingly the anions (ESI neg.). The determination of the molar mass and the total formula are possible. Information about the structure of the cations could be obtained by using the ion-molecule-push-process. The cations decomposed in the typical fragmentation pathway are formed in Scheme 81b. 

This formula can push toxin outward and discharge pus. It is used for treating an abscess that leads to a chronic process. The abscess is accompanied by localized pain, swelling, heat and production of pus but without signs of perforation. This is because the Qi is deficient and it is unable to push the toxin outward and discharge the pus. Instead, an abscess is formed under the skin. The accumulated toxin creates pain, swelling and heat. 

In Williamson s vivid conception, this process happens continuously and randomly, promoted by the constant kinetic motion of the molecular participants and pushed to completion by the stability of the resulting products, ether and water, and their removal from the site of reaction. He illustrated his mental vision of this molecular dance by means of formula tableaux that made clear the various displacements of the ethyl radicals. His paper thus contains what is probably the first competent and empirically plausible proposal for an important reaction mechanism, a viewpoint that was founded upon the "broader basis of atomic motion."... 

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