Purity and Homogeneity Assessment

PAMAM dendrimers provide a series of nearly precise macromolecules with almost equivalent charge density, yet a wide molecular weight range (a few hundred to almost a million), of which gel electrophoretic analysis can be carried out under native conditions [21], 

For comparison, linear and dendritic poly(lysine)s were analyzed in a parallel study using PAGE [21], The linear poly(lysine), with a reported polydispersity of 

In a recent report, the divergent solid-phase synthesis of nucleic acid dendrimers was also reported and the purity assessed using PAGE [24], however, the details are not included here due to space constraints. 

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