Psychotropic agents olanzapine

Of 14 consecutive patients with bipolar I disorder, who were inadequately responsive to standard psychotropic agents and who were given olanzapine, 8 improved (20). The most common adverse effects were sedation, tremor, dry mouth, and increased appetite with weight gain. 

Olanzapine is a psychotropic agent that belongs to the thienoben-zodiazepine class. Olanzapine (ZYPREXA Eli Lilly and Company) is approved by the U.S. Food and Drug Administration (FDA) for treating the symptoms of schizophrenia and acute mixed, manic episodes, or maintenance treatment of bipolar disorder. Quetiapine... 

The newer atypical psychotropics vary widely in their receptor binding profiles. Olanzapine and quetiapine bear resemblance to the profile of clozapine in that their therapeutic effects appear to derive from action on different receptors and transmitter systems. All atypicals (except amisulpride) exhibit greater antagonism of SHT -receptors than Baroceptors compared with the classical agents. Atypical drugs that do antagonise dopamine D -receptors appear to have affinity for those in the... 

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