Pseudopterogorgia bipinnata

Scheme 2 Terpenoid carbon skeletons from Pseudopterogorgia bipinnata.

Also included among the cembrolides is the 14-membered furanocembrolide, namely acerolide, 87, which was isolated and characterized by Chan et al [50]. Related 14-membered cyclic cembrolides include compounds 88 a-c and 89 isolated from Pseudopterogorgia bipinnata. Shown in scheme 7 is a total synthesis of 87 proposed by Astles and Paquette [55]. 

Investigation of the products of Pseudopterogorgia bipinnata by Wright [56] and coworkers yielded a new class of cembrenoids, namely, bipinnatins 88 a-c and 89. 

Ospina, C.A., Rodriguez, A.D., Sanchez, J.A., Ortega-Barria, E., Capson, T.L., and Mayer, A.M.S. (2005) Caucanolides A-F, unusual antiplasmodial constituents from a Colombian collection of the gorgonian coral Pseudopterogorgia bipinnata. J. Nat. Prod., 68, 1519-1526. 

Rodriguez, A.D. and Shi, J. (1999) Isolation, structure elucidation and synthesis of bisgersolanolide, a novel heptacyclic bis-diterpenoid from the gorgonian octocoral Pseudopterogorgia bipinnata. Org. Lett., 1, 337-340. 

Rodriguez, A.D. and Shi, YP. (2000a) New metaboUtes from the West Indian sea feather Pseudopterogorgia bipinnata. J. Nat. Prod., 63, 1548-1550. 

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