Pseudo-receptor models

CHAPTER 28 Pharmacophore Identification and Pseudo-Receptor Modeling 

FIGURE 28.5 Molecules used to generate the pharmacophore for inducers of fetal hemoglobin. 

FIGURE 28.6 Molecular structures of the two most active inducers identified by the pseudo-receptor. 

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Vedani A, Zbinden P, Snyder JP. Pseudo-receptor modeling a new concept for the three-dimensional construction of receptor binding sites. J Recept Res 1993 13 163-177. 

C. Importance of the B. Pseudo-receptor models screening of compound... 

CHAPTER 28 Pharmacophore Identihcation and Pseudo-Receptor Modeling... 

Bohacek, R., Boosalis, M. S., McMartin, C., Pallet, D. V., Perrine, S. P. Identification of novel small-molecule inducers of fetal hemoglobin using pharmacophore and PSEUDO receptor models. Chem. Biol. Drug Des. 2006, 67, 318—328. 

A. Vedani, P. Zbinden, J. P. Snyder, and P. A. Greenidge,/. Am. Chem. Soc., 117,4987 (199,5). Pseudo-receptor Modelling. The Construction of Three-Dimensional Receptor Surrogates. 

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