PRR Arrays on Mononuclear Phagocytes

The differential e q ression ofPRRs on di rent mononuclear phagocytes results in a cell-type specific response and hence further increases the specificity of innate immune responses to 

Receptor Deficiency Pathogen Morphotype Route of Infection Su ceptibility to Infection Reference 

TLR4 C. albicans Hyphae Intravenous Not increased (survived longer than WT) 4 

TLR2 C. albicans Yeast Intravenous More resistant 65 

TLR2 A. fumigatus Conidia Intranasal More resistant 4 

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