Protonated from substitution reactions with organometallic

Part V is devoted to the study of H transfers in organic and organometallic reactions and systems. In Ch. 18 Koch describes kinetic studies of proton abstraction from CH groups by methoxide anion, of the reverse proton transfer from methanol to hydrogen bonded carbanion intermediates, and of proton transfer associated with methoxide promoted dehydrohalogenation reactions. Substitutent effects, kinetic isotope effects and ah initio calculations are treated. Of great importance is the extent of charge delocalization in the carbanions formed which determine the kinetic and thermodynamic acidities. 

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