Proton transfer reaction mass spectrometry drift tube

Proton transfer reaction mass spectrometry (PTR-MS) was first developed at the Institute of Ion Physics of Innsbruck University in the 1990s. Nowadays, PTR-MS is a well-developed and commercially available technique for the on-line monitoring of trace volatile organic compounds (VOCs) down to parts per trillion by volume (ppt) level. PTR-MS has some advantages such as rapid response, soft chemical ionization (Cl), absolute quantification, and high sensitivity. In general, a standard PTR-MS instrument consists of external ion source, drift tube, and mass analysis detection system. Figure... 

Hanson, D.R., Greenberg, J., Henry, B.E., Kosciuch, E. (2003) Proton transfer reaction mass spectrometry at high drift tube pressure. International Journal of Mass Spectrometry, 223,507-518. 

Shen, C.Y, Li, J.Q., Wang, Y.J., Wang, H.M., Han, H.Y, Chu, YN. (2010) Discrimination of isomers and isobars by varying the reduced-field across drift tube in proton-transfer-reaction mass spectrometry (PTR-MS). Inter-... 

Keck, L., Oeh, U., Hoeschen, C. (2007) Corrected equation for the concentrations in the drift tube of a proton transfer reaction-mass spectrometer (PTR-MS). International Journal of Mass Spectrometry, 264, 92-95. 

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