Proton transfer reaction mass spectrometry applications

PROTON TRANSFER REACTION MASS SPECTROMETRY APPLICATIONS IN THE LIFE... 

Crespo, E. (2012) Proton transfer reaction-mass spectrometry, applications in life sciences PhD dissertation. Radboud University, Nijmegen. 

Lindinger, W., Fall, R., Karl, T.G. (2001) Environmental, food and medical applications of proton-transfer-reaction mass spectrometry (PTR-MS). Adv. Gas Phase Ion Chem. 4 1-48. 

Zhan, X., Duan, J., Duan, Y. Recent developments of proton-transfer reaction mass spectrometry (PTR-MS) and its applications in medical research. Mass Spectrom. Rev. 32, 143-165 (2013)... 

The development of proton-transfer-reaction mass spectrometry (PTR-MS) as a tool for the analysis of volatile organic compounds (VOCs) is described. PTR-MS is based on the rapid, non-dissociative transfer of protons from H30 to most common VOCs, but not to the principal gases in the air sample. Recent developments in the design of PTR-MS instruments allow detection of some VOCs in the parts per trillion by volume range. This sensitivity and the capability of PTR-MS instruments to be operated for extended periods in both laboratory and field settings has allowed exploration of many aspects of VOC analysis in environmental, food and medical applications. 

We have briefly mentioned the use of data on IMR in plasma modeling and for the understanding of interstellar molecular synthesis as well as of ionospheric chemistry, and we also want to point out the applications of IMR in various methods of chemical ionization. The most recent one, developed in our laboratory, namely proton-transfer reaction mass spectrometry (PTR-MS), allows for on-line monitoring of volatile organic compounds at levels as low as a few parts per trillion and is therefore applicable for environmental, food, and medical research involving investigations of fast metabolic and enzymatic processes. 

Ellis, A.M., Mayhew, C.A. (2013) Proton Transfer Reaction Mass Spectrometry Principles and Applications. John Wiley Sons, Ltd, Chichester. 

Hewitt CN, Hayward S, Tani A. The application of proton transfer reaction mass spectrometry (PTR-MS) to monitoring and analysis of volatile organic compounds in the atmosphere. J Environ Monit. 2003 5 1-7. 

Hansen MJ, Liu D, Guldberg LB, et al. Application of proton transfer reaction-mass spectrometry to the assessment of odorant removal in a biological air cleaner for pig production. J Agric Chem. 2012 60 2599-606. 

By combining the principles of PICI with an apparatus derived from selected-ion flow tube (SIFT) experiments, the technique of proton transfer reaction mass spectrometry (PTR-MS) has been developed as a dedicated tool for the analysis of volatile organic compounds (VOCs) at parts-per-trillion by volume (pptv) level in air [51,52]. PTR-MS is highly useful as a fast and quantitative method for the determination of VOCs as proven by numerous applications in food control, envi-... 

Lindinger, W. Hansel, A. Jordan, A. Online Monitoring of Volatile Oiganic Compounds at Pptv Levels by Means of Proton-Transfer-Reaction Mass Spectrometry (PTR-MS). Medical Applications, Food Control and Environmental Research. Int. J. Mass Spectrom. Ion Proc. 1998, J7J, 191-241. 

Jensen, N. R. V., Karl, T., Prazeller, P. et al. (2003) Contribution International Conference on Proton-Transfer Reaction Mass Spectrometry and Its Applications. 

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