Proteins ganoderma

Ling Zhi-8 (LZ-8) is an immunomodulatory protein (29,30) isolated from the mycelial extract of Ganoderma lucidium, that has been purified and shown to stimulate mouse spleen and human peripheral blood lymphocytes. LZ-8 is able to inhibit antibody production and prevent the development of autoimmune type I diabetes in NOD mice. 

Other natural sources of anti-HSV PS include fungi, e g., various protein bound PS isolated from Ganoderma lucidum, a basidiomycetous fungus used to treat human diseases in oriental folk medicine [98], The possible mode of antiviral activity of these PS seems to be related to their binding with HSV-specific glycoproteins responsible for attachment and... 

Canodermin, an antifungal protein (Mr 15 kDa) from fruiting bodies of the medicinal mushroom Ganoderma lucidum. Gan-odermin inhibited the mycelial growth of Botrytis cinera, Fusarium oxysporum, and Physalospora piricola [H. Wang, T. B. Ng, Peptides 2005, 27, 27]. 

Protein bound polysaccharides Exhibited potent HSV-1 and HSV-2 antiviral activity Ganoderma lucidum Eo et al. (2000) and Liu et al. (2004)... 

Eo SK, Kim YS, Lee CK et al (2000) Possible mode of antiviral activity of acidic protein bound polysaccharide isolated from Ganoderma lucidum on herpes simplex viruses. J Ethnopharmacol 72 475-481... 

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