Proteins chitinases

The resemblance between grape and PR proteins (chitinase and thaumatin) does not prove that they are identical molecules. In fact, none of the proteins in grapes have the extreme sweetening properties of thaumatin and thaumatin and chitinase antibodies do not react with grape proteins (Pigarra-Pereira et al, 1998). 

Hakala BE, White C, Recklies AD 1993 Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family. J Biol Chem 268 25803-25810... 

Hu B, Trinh K, Figueira WF, Price PA 1996 Isolation and sequence of a novel human chondrocyte protein related to mammalian members of the chitinase protein family. J Biol Chem 271 19415-19420... 

Fig. 10.5. Immunoblotting analysis of the antibody response of jirds against various stages of A viteae. (A) Reaction with sera of jirds vaccinated with irradiated L3 (B) reaction of sera of A. w feae-infected jirds (C) reaction with sera of naive jirds. 1, Male antigens 2, female antigens 3, mf antigens 4, L3 antigens. Note that the reaction of vaccinated jird sera is predominantly directed against chitinase bands of 205 kDa and 67 kDa (arrows) as well as against a 17 kDa protein.

Blaak, H., Schnellmann, J., Walter, S., Henrissat, B. and Schrempf, H. (1993) Characteristics of an exochitinase from Streptomyces olivaceoviridis, its corresponding gene, putative protein domains and relationship to other chitinases. European Journal of Biochemistry 214, 659-669. 

Henrissat, B. (1990) Weak sequence homologies among chitinases detected by clustering analysis. Protein Sequence Data Analysis 3, 523-526. 

Renkema, G.H., Boot, R.G., Muijsers, A.O., Donker-Koopman, W.E. and Aerts, J.M.F.G. (1995) Purification and characterization of human chitotriosidase, a novel member of the chitinase family of proteins. Journal of Biological Chemistry 270, 2198-2202. 

Tellam, R.L. (1996) Protein motifs in filarial chitinases an alternative view. Parasitology Today 12, 291-292. 

Volck, B., Price, P.A., Johansen, J.S., Sorensen, O., Benfield, T.L., Nielsen, H.J., Calafat, J. and Borregaard, N. (1998) YKL-40, a mammalian member of the chitinase family, is a matrix protein of specific granules in human neutrophils. Proceedings of the Association of American Physicians 110, 351-360. 

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