Protein ortholog

K17. Kershaw, D. B., Beck, S. G., Wharram, B. L., Wiggins, J. E., Goyal, M., Thomas, P. E., and Wiggins, R. C., Molecular cloning and characterization of human podocalyxin-like protein. Orthologous relationship to rabbit PCLP1 andratpodocalyxin. J. Biol. Chem. 272,15708—15714... 

Fig. 4.8 Protein family/disease ortholog view of the Drosophila protein-interaction map. Proteins are color-coded according to protein family as annotated by the Gene Ontology hierarchy. Proteins orthologous to human disease proteins have a jagged, starry border. Interactions were sorted ac-...

Frizzled (Fz) proteins comprise a family of seven-pass transmembrane receptors with a cysteine-rich extracellular domain. As a class, Fz proteins are structurally related to the superfamily ofheterotrimeric G-protein coupled receptors (GPCRs). Diere are 4 Fz genes in Drosophila and 10 in humans, with close orthologs... 

Sakudoh, T., Tsuchida, K., and Kataoka, H. 2005. BmStartl, a novel carotenoid-binding protein isoform from Bombyx mori, is orthologous to MLN64, a mammalian cholesterol transporter. Biochem. Biophys. Res. Commun., 336(4) 1125—1135. 

Murray and Hunt, 1993). Cyclins, kinases, and phosphatases that regulate the passage of the cell through the G] — S phase transition are all present in mammals, invertebrates, and plants (Solomon, 1993 Doonan and Fobart, 1997 Zavitz and Zipursky, 1997). However, multicellular eukaryotes contain multiple orthologs of yeast cell cycle proteins they initiate proliferation via growth factors, rather than, for example, yeast mating factors, and they possess additional checkpoint controls and repair pathways. 

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