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Protein Modification Screening

The key feature of the PDA technology is that a far wider biological diversity can be screened computationally than it is possible with exclusively experimental methods. The in silico approach provides unique and original gene modifications whilst maintaining the precise control over the extent and nature of protein modifications. The novel sequences... [Pg.276]

This pathway, which is driven by the presence of free Gfly, was modified to allow for screening of mammalian cDNA expression libraries to isolate those cDNAs that activated transcription of a pheromone-responsive promoter downstream of activated G-protein. Modifications included eliminating the pheromone receptor, replacing the endogenous yeast Ga... [Pg.60]


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Protein Modification Screening Tool

Proteins, modification

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