Protein lipid complex, disadvantages

Lipids are often a nuisance in extraction of proteins. For example, in preparing leaf protein concentrate a protein-lipid complex is formed frequently affecting the protein extraction efficiency (16). Nutritionally, the complex is disadvantageous because it resists digestion by proteases (17). Shenouda and Pigott (18) found that the formation of protein-bound lipids can cause a low efficiency of extraction of protein from fish. Hydro-phobic bonding probably plays an important role in protein-lipid interactions. Mohammadzadeh-k et al. (19) reported protein interaction with completely apolar compounds such as aliphatic hydrocarbons. 

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