Protein engineering activator creation

The examples above represent some of the most successful studies in protein engineering. They show that it is possible to enhance protein thermostability rationally, alter cofactor or substrate specificity, regiospecificity, and even change catalytic activity. Furtherm ore, the creation of enzymatic activity from a non-catalytic protein backbone, and the creation of a biocatalyst with an unprecedented catalytic activity not found in nature, have also been achieved. However, the examples published in the literature are probably only a tiny fraction of the many studies that have been, or are still, in progress awaiting positive results. 

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