Protein biological processes influenced

Table I. Biological Processes Influenced by Proteins at Interfaces...

Heparinoid polysaccharides such as heparan sul te and heparin are able to interact with numerous proteins and influence vital biological processes. Heparinoid mimetics were prepared to reduce the structural complexity of heparinoids and to obtain selectivities. This artide summarizes the development of heparinoid mimetics of different classes including representative syntheses and biological activities. Largely simplified compounds with regard to structure and synthetic access are described which maintain or exceed the activity of heparinoid polysaccharides. One of the recipes to increase binding or modify pharmacokinetic parameters was the introduction of hydrophobic groups. 

Wroblewska, B. and Jedrychowski, L. 2002a. Influence of technological and biological processes on the immunoreactivity of cow milk proteins. Pol J Food Nutr Sci 11/52 (SI 2) 156-159. 

Enzymes are proteins that act as catalysts, speeding the rate at which biochemical reactions proceed but not altering the direction or nature of the reactions. The presence or absence of these important substances affects the biochemical conditions, which then influence the other physiologic processes in the body. Enzyme deficiencies are often inherited as autosomal recessive conditions and may be passed from parent to child. Clearly, when students begin to understand the role of the enzyme and the chemical reaction that it governs, they begin to nnderstand the intricacies of the human biological processes. 

Adsorbed proteins influence and are important in a variety of biological processes, as illustrated by many examples. 

Since the discovery of Ub (Schlesinger et al, 1975) more than 20 years ago, ubiquitination (Hershko et al., 1983) has become one of the cornerstones of covalent protein modification. An explosion of research in the area in the last 10 years has revealed biological roles for ubiquitination that rival the scope of phosphorylation. Because its traditional and best-characterized role is a fundamental biological process found in eukaryotes, namely, proteasome-dependent protein deg radation, it is not surprising that ubiquitination has such a broad cellular influence. More recendy, however, breakthrough discoveries in the field have revealed an even greater depth and versatility, several examples of which are encountered in the PRR pathway. 

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