PROTEAN

Adachi, K., 1983. Calculation of strain histories in Protean coordinate systems, Rheol. Acta 22, 326-335. 

Some Chemical Considerations Relevant to the Mouse Bioassay. Net toxicity, determined by mouse bioassay, has served as a traditional measure of toxin quantity and, despite the development of HPLC and other detection methods for the saxi-toxins, continues to be used. In this assay, as in most others, the molar specific potencies of the various saxitoxins differ, thus, net toxicity of a toxin sample with an undefined mixture of the saxitoxins can provide only a rough approximation of the net molar concentration. Still, to the extent that limits can be placed on variation in toxin composition, the mouse assay can in principle provide useful data on trends in net toxin concentration. However, the somewhat protean chemistry of the saxitoxins makes it difficult to define conditions under which the composition of a mixture of toxins will remain constant thus, attaining a reproducible level of mouse bioassay toxicity is difficult. It is therefore useful to review briefly some of the chemical factors that should be considered when employing the mouse bioassay for the saxitoxins or when interpreting results. Similar concepts will apply to other assays. 

Warner RM, Srinivasan JR (2004) Protean manifestations of intravenous drug use. Surgeon 2(3) 137-140... 

In conclusion, H3 ligands offer the attractive vista of multiple applications in various disorders, but the ultimate definition of their therapeutic utility will have to await clinical trial results. Future work will determine whether inverse agonists, neutral antagonists, or protean agonists will constitute the more useful pharmacological intervention. 

Kenakin T., Inverse, protean, and ligand-selective agonism matters of receptor conformation, FASEB J., 15(3), 598-611, 2001. 

In addition, there is growing evidence for illnesses caused by genes whose product is an RNA molecule, not a protein per se. Also, the protean manifestations of RNA molecules and their modifications (including RNA editing) may contribute to our understanding of disease [82, 101-103],... 

Grenier, G., L. Protean, J.P. Marier, and G. Beaumont. 1987. Effects of a sublethal concentration of atrazine on the chlorophyll and lipid composition of chlorophyll-protein complexes of Lemna minor. Plant Physiol. Biochem. 25 409-413. 

Miller, G. Evolution of the Human Brain Through Runaway Sexual Selection The Mind as a Protean Courtship Device. PhD thesis, University of California. 

Figure 8.1 Exploded view of an electrophoresis cell. The components of the Bio-Rad Mini-PROTEAN 3 are shown. The inner chamber can hold one or two gels. It contains an electrode assembly and a clamping frame. The interior of the inner assembly constitutes the upper buffer compartment (usually the cathode compartment). The chamber is placed in the tank to which buffer is added. This constitutes the lower (anode) buffer compartment. Electrical contact is made through the lid.

Todd, J.S. Protean, P.J. Gerwick, W.H. (1994) The absolute configuration of ecklmiialactones A, B, and E, novel oxylipins from brown algae of the gaiera Ecklonia and Egregia. J. Nat. Prod., 57,171-4. 

SDS-polyacrylamide gel electrophoresis Protein samples were analyzed under denaturing conditions in a discontinuous gel system as described by Laemmli [13] using a 5% stacking gel and a 12% separating gel in a vertical gel system (BioRad, Mini Protean 11, CA, USA). 

SDS-PAGE system called DALT in 1975 to provide this benefit. Investigator and Protean II are the new versions of such systems. 

To test this idea, a Bio-Rad Protean II electrophoresis cell and Bio-Rad Model 3000xi computer-controlled power supply were used to carry out the electrophoretic separation and recovery of pre-stained and unstained protein calibration standards (lysozyme, soybean trypsin inhibitor, carbonic anhydrase, ovalbumin, bovine serum albumin and phosphorylase B) obtained from Bio-Rad Laboratories. Standard SDS-gel electrophoresis techniques were used [167]. 

Phosphorus is one of the most remarkable of the many remarkable substances known to the chemist. The curious method of its discovery, the universality of its distribution, its intimate connection with the phenomena of animal and vegetable life, its extraordinary physical properties and chemical activity, its abnormal molecular constitution, the protean ease of its allotropie transformation, all combine to make up a history which abundantly justifies its old appellation of the phosphorus miraibilia.—T. E. Thorpe. 

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