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Prostaglandin transdermal delivery

Adachi, H. Irie, T. Uekama, K. Manako, T. Yano, T. Saita, M. Combination effects of O-carboxymethyl-O-ethyl-P-cyclodextrin and penetration enhancer HPE-101 on transdermal delivery of prostaglandin Ej in hairless mice. Eur. J. Pharm. Sci. 1993, 1, 117-123. [Pg.1323]

Uekama, K., Adachi, H., Irie, T. et al. Improved transdermal delivery of prostaglandin Ei through hairless mouse skin combined use of carboxymethyl-ethyl-(3-cyclodextrin and penetration enhancers. J. Pharm. Pharmacol. 1992, 44, 119-121. [Pg.839]

Topical delivery of diclofenac in 2.5% HA has also been shown to inhibit the development and angiogenesis of colon-26 adenocarcinoma (112). In this work, HA-diclofenac reduced proliferation and viability of colon-26 adenocarcinoma cells in vitro, inhibited tumor prostaglandin synthesis, and retarded angiogenesis in mice (114). Analysis of the tumor vasculature showed that vascular development was retarded by 12 days. The effects of HA-diclofenac were likely related to enhanced transdermal delivery and binding properties of HA. [Pg.344]


See other pages where Prostaglandin transdermal delivery is mentioned: [Pg.664]    [Pg.830]   


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