Propionaldehyde dehydrogenase

Luo LH, Kim CH, Heo SY, Oh BR, Hong WK, Kim S, Kim DH, Seo JW. (2012). Produe-tion of 3-hydroxypropionic acid through propionaldehyde dehydrogenase PduP mediated biosynthetic pathway in Klebsiella pneumoniae. Bioresour Technol, 103,1-6. 

Reactions of Triose Phosphate Dehydrogenase. This enzyme is not specific in its reaction with phosphoglyceraldehyde. The nonphospho-rylated compound is oxidized also, but only at 0.1 per cent of the rate found with the natural substrate. Acetaldehyde, propionaldehyde and butyraldehyde are also oxidized, but at still slower rates. The corresponding acyl phosphates are formed when these substrates are oxidized in the presence of inorganic phosphate. If arsenate is substituted for phosphate, the reactions proceed not to equilibrium, but to completion, with the formation of free acids. The formation of free acids is presumed to be the result of rapid spontaneous hydrolysis of unstable acyl arsenates, as proposed for other arsenolysis reactions. 

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