2-Propanone, 1-chloro-3-phenyl

Propanone, 1-phenyl- [Benzyl methyl ketone), 55,94 Propene, 0 >l-bromo- 55, 108 Propene, (Z)-l-bromo- 55, 108 Propene, (F) 1 chloro-, 55, 104 Propene, (Z) 1 chloro, 55, 107 2-PROPENENITRILE, 2-(l,l-dimcthylethyl)... 

BENZYL CHLOROMETHYL KETONE (2-Propanone, l-chloro-3-phenyl-)... 

Chloro-1-phenyl-1-propanone 2-Chloroethyl phenyl ketone CgHgCIO 936-69-4 168.619 11 (eth), cry (al, peth) 49.6 113" ... 

Normally water-insoluble drugs with a phenyl ring can form molecular complexes with surfactants. The chemical structures of l-(2,4,6-trihydroxyphenyl)-l-propanone (flopro-pione), an anti-spasmodic, and 4-chloro-m-cresol (a germicide) are shown in Figure 4.34. They became soluble in aqueous solutions in the presence of surfactants, probably because of complex formation. In order to understand the nature of complex formation, the cationic surfactants CTAB and MTAB were used. The complex crystals between CTAB and 4-chrolo-m-cresol (XXIII), MTAB and flopropione (XXIV), and CTAB and flopropione (XXV) were obtained from the solutions of methanol, methanol and aqueous solutions, respectively. 

As in lutidine-methanol, l-chloro-2-propanone undergoes methanolysis much more slowly than does 29c this difference in reactivity is due to the effect of the two phenyl groups in zwitterion 32. ... 

Oxime [344367-93-7] C Hj BrNOj mol.wt. 288.14[7273], 1 -(5-Chloro-3-ethyl-2-hydroxy phenyl)- -propanone... 

Chloro-6-hydroxy-3-melhyl-7-(l-oxopropyl)benzofuran, 1994 l-[2-Hydroxy-4-(l-methylethyl)phenyl]-l-propanone-2,2,5,5,5-d5, 1858... 

Chloro-2,4-diliydroxy-3-(l-oxopropyl)benzoic acid, 1779 [102553-89-9] l-[2-Acetyl-5,6-dimetlioxy-3-(phenylmethoxy)phenyl]-l-propanone, 2141... 

Benzyl chloride, carbon tetrachloride, allyl chloride, and also 3-chloro-l-phenyl-1-propanone with triethyl phosphate and trimethyl phosphite in the presence of neutral alumina afforded the desired products in excellent yields with microwave irradiation. The t-butyl chloride failed in this condition and no Arbuzov rearrangement product was detected. The other types of alumina (acidic and basic) were not as effective as neutral alumina and usually give relatively low yields of the corresponding products. Simple work-up, low consumption of solvent, fast reaction rates, mild reaction condition, and good yields of the reaction make this method an attractive and useful contribution to the present methodologies. 

---