2-propanol radiation chemistry

Although the radiation-induced oxidation of ethanol has been fully in-- vestigated (2, 22, 23), little work has been published on the oxidation of other alcohols. In connection with a project concerned with the relative rates of hydroxyl radical reactions using 2-propanol as reference solute, it was thought desirable first to investigate the radiation chemistry of 2-propanol-oxygen solutions both in aqueous solution and pure 2-propa-nol. The results of this investigation are presented here. 

Steenken S, Jovanovic SV, Candeias LP, Reynisson J (2001) Is frank" DNA-stand breakage via the guanine radical thermodynamically and sterically possible Chem Eur J 7 2829-2833 Steinmaus H, Rosenthal I, Elad D (1969) Photochemical and y-ray-induced reactions of purines and purine nucleosides with 2-propanol. J Am Chem Soc 91 4921-4923 Steinmaus H, Rosenthal I, Elad D (1971) Light- and y-ray-induced reactions of purines and purine nucleosides with alcohols. J Org Chem 36 3594-3598 Stelter L, von Sonntag C, Schulte-Frohlinde D (1974) Radiation chemistry of DNA-model compounds, V. Phosphate elimination from ribose-5-phosphate after OH radical attack at C-4. Int J Radiat Biol 25 515-519... 

The radiation chemistry of 2-propanol is analogous to that of methanol, that is, the main reactive species are Cs and (CH3)2 COH. In alkaline solution, (CH3)2 COH deprotonates to (CH3)2CO . In the presence of N2O or acetone, es is converted to (CH3)2 C0H/(CH3)2C0 by the reactions in Eqs. 30 and 18, or the reaction of Eq. 20, respectively. The solvated electron in 2-propanol has been utilized to study electron-transfer reactions between aromatic radical anions (donor) and aromatic molecules (acceptor) [16]. The donor-acceptor pairs studied were pyrene-anthracene, pyrene-9,10-dimethylanthracene and w-terphenyl-/ -terphenyl. In the first two cases an equilibrium was established and the parameters forward and kback were measured this was the first example of the measurement of an equilibrium constant by use of pulse radiolysis. The rate constants for the electron-transfer reactions were examined in terms of the Marcus theory [17]. 

The radiation chemistry of 2-propanol is analogous to that of methanol the major reducing radicals are e and (CH3)2 COH, and (CH3)2 CO in alkaline solution. This solvent has been used to investigate the one-electron reduction of fuHerenes. For example, reduction of Cgg, which is insoluble in water, by e and (CH3)2 COH generates Qg which is stable for hours in the absence of oxygen. 

In most cases, an aqueous solution of the quinone has been used for radiation chemical studies. However, the reaction sequence depends entirely on the added scavengers like sodium formate, methanol, 2-propanol, tert-butanol or others. In om own work, we have extensively used a relatively novel solvent system comprising of a mixture of 2-propanol (5 mol dm ) and acetone (1 mol dm ) in water (32.5 mol dm ). The advantage of this system, over and above solubilizing quinones insoluble in water, lies in the chemistry involved [26,27], so that (CH3)2C 0H radical is produced as an exclusive reducing agent. 

Z. Han, Y. Katsumura, et al., Effect of Temperature On the Absorption Spectra of the Solvated Electron in 1-Propanol and 2-Propanol Pulse Radiolysis and Laser Photolysis Studies at Temperatures Up to Supercritical Condition, Radiation Physics and Chemistry, Vol. 77, 409 15 (2008)... 

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