Propanedioate esters, acidity

Esters of propanedioic (malonic) acid can be alkylated in a similar fashion (Equation 18-20) ... [Pg.833]

Alkyl-substituted 3-oxobutanoic and propanedioic esters can be hydrolyzed under acidic conditions to the corresponding acids, and when these are heated they readily decarboxylate (Section 18-4). Alkyl 3-oxobutanoic esters thus yield methyl alkyl ketones, whereas alkylpropanedioic esters produce carboxylic acids ... [Pg.834]

Esters of. most dicarboxylic acids, except propanedioic esters, undergo the Claisen condensation in much the same way as do esters of monocarboxylic... [Pg.851]

Dimethyl 1,3-Propanedioate Malonic acid, dimethyl ester (8) Pro-panedioic acid, dimethyl ester (9) (108-59-8)... [Pg.116]

In Section 23-2 two reactions of /3-tlicarbonyl compoiiiiJs arc presented. The (irst is alkylation of the readily deprotonated "carbon in the middle." The second pertains to /3-dicarbonyi compounds where at least one of the carbonyl groups is an ester. Ester hydrolysis leads to a carboxylic acid that readily loses COi (decarboxylation). When this sequence is carried out on a /3-ketocster, the result is a ketone. When carried out on a diester of propanedioic (malonic) acid, the result is a carboxylic acid. In each case, groups attached in the preliminary alkylation slep(s) wind up in the product. [Pg.482]

Synonyms Dimethyl propanedioate Dimethyl 1,3-propanedioate Malonic acid, dimethyl ester Methyl malonate Propanedioic acid, dimethyl ester... [Pg.1434]

Loss of CO2 occurs readily only from the neutral carboxylic acid. If the ester is hydrolyzed with base, acid must be added to protonate the resulting carboxylate salt in order for decarboxylation to occur. Decarboxylation of substituted propanedioic (malonic) acids follows the same mechanism. [Pg.1050]

Acetamido-2-(7-chloroindol-3-ylmethyl)propanedioic acid dimethyl ester[6]... [Pg.62]

C2()H29NOi 94868-25-4) see Oxypyrronium bromide a-cyclohexylphenylglycolic acid propargyl ester (C12H20O3 81039-74-9) see Oxybutynin [(4-cyclohexylphenyl)methylene]propanedioic acid diethyl ester... [Pg.2341]

Di-fcr(-butyl diazomalonate Malonic acid, diazo-, di-(erf-butyl ester (8) Propanedioic acid, diazo-, bis(l,l-dimethylethyl)ester (9) (35207-75-1)... [Pg.36]

Dimethyl (1, R,2 R,5,R)-2-(2 -isopropenyl-5 -methylcyclohex-1 -yl)-propane-1,3-dioate Propanedioic acid, [5-methyl-2-(1-methylethenyl)cyclohexyl]-, dimethyl ester, [1R-(1a,2p,5o)]- (12) (106431-81-6)... [Pg.88]

Dimethyl mesoxolate Propanedioic acid, oxo-, dimethyl ester (9) (3298-40-6) Dimethyl benzalmalonate Malonic add, benzylidene-, dimethyl ester (8) Propanedioic add, (phenylmethylene)-, dimethyl ester (9) (6626-84-2) Dimethyl sulfide Methyl suflide (8) Methane, thiobis- (9) (75-18-3)... [Pg.246]

Propanedioic acid, diethyl ester (105-53-3), 66, 179 Propanedioic acid, (methoxyraethylene)-, dimethyl ester, 65, 98 Propanedioic acid, (3-methyl-2-butenyl)-, dimethyl ester ... [Pg.130]

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