13-Diamino propane

A range of bis- and tris-spirocyclic cyclotriphosphazenes 182-187 containing bi-2-napthoxy, 2,2 -biphenoxy, 2,2-dimethyl-1,3-propane diamino, and 2,2-dimethyl-1,3-propane dioxy ligands have been prepared from the appropriate diamines and diols <2004POL979>. 

In an analogous fashion the oxidative coupling of 1,3-diselenols is used for the preparation of 1,2-diselenolanes, the precursors being obtained by a variety of methods (see Chapter 4.35). Similar reaction s have been used for the preparation of 1,2-thiaselenolanes. Substituted propane-1,3-diselenones (287) are oxidized by halogen to the corresponding 3,5-diamino-l,2-diselenolylium chloride (288) (67AJC1991). 

Zur Reduktion von Harnsaure und seinen N-Alkyl-Derivaten s. S. 597 Auch 2,3-Dihydro-1,4-diazepinium-Salze werden in Athanol/Perchlorsaure an Kupfer im wesentlichen zu 1,4-Diazepanen reduziert. Wahrend beim 1,4-Diphenyl-Derivat hauptsachlich das Ringsystem erhalten bleibt, erhalt man aus dem 5,7-Diphenyl-Derivat unter Ringspaltung 1,2-Diamino-athan, 3-Oxo-l,3-diphenyl-propan und Chalkon3 ... 

When M is Mo or W, the substitution reaction follows a two-term rate expression and in addition there is some replacement of the dipyridyl or 1,2-diamino-2-methyl propane but not of o-phenanthroline. The proportion of bidentate replacement to CO replacement is practically independent of the concentration... 

An interesting pyrrolo[l,2-tf]pyrimidine was described as the product of the reaction of the heterocyclic ketene-aminals 236 that was synthesized by cyclocondensation of ketene dithioacetals 237 and 1,3-diamino propane. These compounds reacted with diethyl oxomalonate that behaves as an hetero-enophile, yielding the corresponding products 238 in acceptable to good yield (Scheme 31). A mechanism that involves an aza-ene reaction, via adduct 239 which isomerizes to ketene aminal 240 to produce the lactam ring of 238, has been proposed <1999J(P1)321>. 

In contrast to NjPjCle, N4P4Q8 is extremely reactive towards difunctional reagents. This has led to the isolation of several decomposition products. Reactions with Af-methyl ethanolamine [87], 1,3-propane diol and 1,3-diamino propane afford mainly spiro products [138]. A detailed investigation on the reactions of N4P4CI8 with HO- CH2) -OH (n = 3, 4) has revealed that... 

In Gegenwart von Palladium-Schwarz reagiert Azetidin bei 120-170° mit der 3fachen molekularen Menge an 1,2-Diamino-ethan, 1,3-Diamino-propan oder Bis-[3-amino-pro-pyl]-amin unter Ringoffnung durch Umalkylierung (vgl. S. 1214f.) zu 1,4,8-Triaza-octan (70%), 1,5,9-Triaza-nonan (73%) bzw. 1,5,9,13-Tetraaza-tridecan (75%)1. 

Equatorial substituents on the C atoms of coordinated 1,3-diamino-propane should be stabilized in the same manner as the 1,2-diaminopropane system and axial substituents on the 1 and 3 C atoms should interact strongly with the axial substituents on the Co atom. Substituents on the N atoms... 

Diamino-1,2-dimethyl propane Diperchlor-SiS or 1,2-Dimothyl-l,3-prvp5ned>ami7>e Di-perchlorate,... 

Diaminopropane (called 1,2-Diamino-propan or Propylendiamin in Ger), CH3.CH(NH2).CH2.NH2 exists as d-form, 1-form dl-form all of which form numerous, cryst salts, some of which are unstable on heating (Ref 1)... 

NOTE Higher nitrated derivs of Diamino-propane were not found in Beil or in CA thru 1961... 

Diamino-2-propanol [called 1,3-Diamino-propanol-(2) l 3-Diamino-2-hydroxy-propan oc j3-Hydroxy-trimethyIenediamin in Ger], H2N.CH2.CH(OH).CH2.NH2 known in the form of salts, some of which are unstable (Ref 1)... 

Hydrated compounds of the type U02(H2L) xH20 have been reported for 1,2-diamino-propane-Af.NjA jAf -tetraacetic acid (x unspecified), tram diaminocyclohexane-N,N,N, N -tetraacetic acid (x = 0 or 3 (U02)2L-xH20, with x = 0 or 6 also known), 2,2 -diaminodiethyl ether-A, A,N, N -tetraacetic acid (x = 3), and 2,2 -diaminodiethyl sulfide-N,N,N, N -tetra-acetic acid (x = 0 or 4) the hydrates are predpitated from aqueous media, but in the last instance a mixture of ethanol and acetone was added to induce precipitation. The analogous di(2-aminoethoxy)ethane-/V, N,N, N -tetraacetic acid (H4L) forms the compounds... 

A more convenient approach for the preparation of a protected Narg derivative is the synthesis of Fmoc-Narg(Boc)2-OH (95 in Scheme 43). The key step in this synthesis is the guanylation of Z-Norn-OMe 93 which can be prepared from a monoprotected diamino-propane with bromoacetate or by reductive amination with glyoxylic acid. 

Dale and Coulon225 reported that heating glutaric acid and 1,3-diamino-propane at 200"C followed by vacuum distillation yielded 6-oxo-2,3,4,7,8,9-hexahydro-6//-pyrido[l,2-a]pyrimidine (178). The piperidine ring homologs of 178 could not be prepared in a similar fashion. Attempts to prepare the pyrido[l,2-fl]pyrimidine (178) by heating the macrocyclic compound (175) in toluene or xylene in the presence of methanesulfonic acid remained unsuccessful.226... 

Iron(II) chelate of bis-N,N-(2-pentanon-4-ylidene)-l,3-diamino-2-hydroxy-propane... 

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