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Promoters hypoxia-response element

Semenza, G.L., B. Jiang, S.W. Leung, R. Passantino, J. Concordet, P. Maire, and A. Giallongo (1996). Hypoxia response elements in the aldolase A, eno-lase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia Inducible Factor-1. J. Biol. Chem. 271 32529-32537. [Pg.156]

Delivery of gene transfer systems of heat shock proteins (Hsp70),250 antioxidant enzymes (catalase)251 or survival genes (Akt)252 has been associated with myocardial protection against ischemia and reperfusion. A vector gene therapy system has also been developed with a hypoxia response element-incorporated promoter to turn on the gene expression in response to hypoxic signal.253... [Pg.63]

Rivera SP, Wang F, Saarikoski ST, Taylor RT, Chapman B, Zhang R, Hankinson O (2007) A novel promoter element eontaining multiple overlapping xenobiotie and hypoxia response elements mediates induetion of cytoehrome P4502S1 by both dioxin and hypoxia. J Biol Chem 282 10881-10893... [Pg.807]

Freeland K, Boxer LM, Latchman DS (2001) The cyclic AMP response element in the Bcl-2 promoter confers inducibility by hypoxia in neuronal cells. Brain Res Mol Brain Res 92(l-2) 98-106... [Pg.287]

Figure 21.9. Human MT promoter. (Adapted from Murphy, B. J., Andrews, G. K. Activation of metallothionein gene expression by hypoxia involves metal response elements and metal transcription factor-1. Cancer Res. 59,1315-1322, 1999.)... Figure 21.9. Human MT promoter. (Adapted from Murphy, B. J., Andrews, G. K. Activation of metallothionein gene expression by hypoxia involves metal response elements and metal transcription factor-1. Cancer Res. 59,1315-1322, 1999.)...

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See also in sourсe #XX -- [ Pg.267 ]




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Hypoxia response

Response elements

Responsive element

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