Promise of Personalized Medicine

Rationale for Customized Drug Therapy Variability and the Present State of Drug Safety and Efficacy in the Clinic 

Rationale for Genetics Can It Explain and Predict Variability in Drug Efficacy and Safety  

Shift in Emphasis on Health Care Policy Toward Disease Prevention 

The dictum in the traditional folklore of medicine has been the treatment and alleviation of acute symptoms of disease. Aforementioned advances in our understanding of the risk factors and molecular basis of human diseases are now paving the way to develop medicines that can prevent or slow the progression of disease phenomena. Schizophrenia and some of the neurodegenerative diseases such as Alzheimer s or Parkinson s disease 

Asymmetry Between Genetics of Human Diseases and Pharmacological Phenotypes An Impetus for Pharmacogenomic Research 

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Silber BM. Pharmacogenomics, biomarkers, and the promise of personalized medicine. In Pharmacogenomics (Ka-low W, Meyer UA, Tyndale RF, Eds.). New York, Basel Marcel Dekker 2001 11-31. 

Mancinelli L, Cronin M, Sadee W. Pharmacogenomics the promise of personalized medicine. AAPS PharmSci 2000 2(1) E4. 

We hope that you will find this book a useful approach to the subject of bioanalytical chemistry and that it will help raise awareness of the vast scope and topics encompassed in what is a rapidly expanding and advancing field. Moreover, we hope that studying the content of this book will provide a fundamental introduction to the tools adopted by life and health scientists in the evolving and exciting new age of omics , with the promise of personalized medicine and novel approaches to the screening, diagnosis, treatment, cure and prevention of disease. 

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