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Prolonged blood circulation

Tan, J. S., D. E. Butter eld, C. L. Voycheck, K. D. Caidwell, and J. T. Li. 1993. Surface modi cation of nanoparticles by PEO/PPO block copolymers to minimize interactions with blood components and prolong blood circulation in rat iomaterials14 823-833. [Pg.371]

In addition to PEGylation, polyvinyl pyrolidone (PVP) nanoparticles modified with hydrophilic polaxa-mine have been reported to adsorb less protein than the unmodified particles, conventional liposomes, and stealth liposomes.Polystyrene microspheres coated with lecithin and particles coated with Pluronic were also observed to adsorb less protein and demonstrate a prolonged blood circulation time without adversely affecting the safety profile of the drug. [Pg.2570]

Kamei S, Kopecek J. Prolonged blood circulation in rats of nanspheres surface modified with semi-telechelic poly [N-(2-hydroxypropyl)methacrylamide]. Pharm Res 1995 12 663-668. [Pg.92]

Sunoqrot, S., Bugno, J., Lantvit, D., Burdette, J.E., Hong, S. Prolonged blood circulation and enhanced tumor accumulation of folate-targeted dendrimer-polymer hybrid nanoparticles. J. Control Release 191, 115-122 (2014). doi 10.1016/ j. jconrel.2014.05.006... [Pg.66]

Critical parameters for prolonged blood circulation of drug carrier... [Pg.71]

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See also in sourсe #XX -- [ Pg.157 ]



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