Progressive decay of behavioral performances

Sexual hormones seem to be responsible for the transition from the developmental, uphill phase of life into the postdevelopmental, downhill period, characterized by the slow age-related decay of brain performance terminated by natural death (Fig. 6 in Knoll 2001). Weighty arguments speak in favor of the assumption that the slow, continuous age-related decline of enhancer regulation in the mesencephalic neurons plays a key role in the progressive decay of behavioral performances with the passing of time (see Sect. 3.5.1.1 for details). 

For the progressive decay of behavioral performances during the downhill period of fife, and... 

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