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Progesterone-dependent enzyme

The steroid Ci7(20)lyase is an enzyme that is involved in the biosynthesis of andro-stenedione and of dehydroepiandrosterone from progesterone and pregnenolone, respectively. As androgen and estrogen hormones are necessary for the growth of tumors, this enzyme is a potential therapeutic target for the treatment of prostate cancer and in hormone-dependent breast cancers. [Pg.268]

James MO, Shiverick KT (1984) Cytochrome P-450-dependent oxidation of progesterone, testosterone, and ecdysone in the spiny lobster, Panulirus argus. Arch Biochem Biophys 233 1-9 James MO, Pouts JR, Bend JR (1977) Xenobiotic metabolizing enzymes in marine fish. In Khan MAQ (ed) Pesticides in aquatic environments. Environmental Science Research, Vol 10. Plenum Press, New York, pp 171-189... [Pg.171]

In the ovary, at least one instance of feedback inhibition has been demonstrated. As in the adrenal, the 17a-hydroxylation of progesterone is catalyzed in the ovary by a NADPH2-dependent microsomal enzyme. There is evidence that progesterone accumulation inhibits the 17a-hydroxylation. [Pg.481]

See other pages where Progesterone-dependent enzyme is mentioned: [Pg.229]    [Pg.229]    [Pg.894]    [Pg.440]    [Pg.212]    [Pg.84]    [Pg.166]    [Pg.86]    [Pg.1253]    [Pg.362]    [Pg.85]    [Pg.242]    [Pg.301]    [Pg.297]    [Pg.268]    [Pg.596]    [Pg.894]    [Pg.107]    [Pg.287]    [Pg.1444]    [Pg.254]    [Pg.1203]    [Pg.312]    [Pg.550]    [Pg.151]    [Pg.340]    [Pg.319]    [Pg.497]    [Pg.150]    [Pg.426]    [Pg.520]    [Pg.180]    [Pg.353]    [Pg.355]    [Pg.837]    [Pg.232]    [Pg.197]    [Pg.988]    [Pg.35]   
See also in sourсe #XX -- [ Pg.229 ]



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Enzyme dependent

Progesteron

Progesterone

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