Production of PHAs by Genetically Engineered Bacteria

The result of an economic analysis was reported for the production of the poly(3HB-co-3HV) copolymer hy a recombinant E. coli strain (Choi and Lee 2000). For this 

A recombinant strain of E. coli was used in the development of a quantitative spectroscopic method for the measurement of poly(3HB) content in the cell (Kansiz et al. 2000). Fourier transform infrared (FTIR) spectroscopy and multivariative statistical methods were performed to determine the cellular poly (3HB) content, and a correlation coefficient of 0.988, with a standard error of 1.49 % poly(3HB), was obtained between the measured and the predicted values. The spectroscopic method circumvented the need to use solvents to extract the PHA before quantitative measurements. 

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