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Problem to Swallow

Sometimes a solid oral preparation needs to be divided or crushed. Normally this is not a problem and problems should be written on the package and in the package leaflet. [Pg.105]

The reason for the problems is often that the characteristics of the medication are changed. Depot formulation loses its slow release properties with increased peak-and decreased through concentrations. Enteric coating is destroyed with stomach [Pg.105]

8 Practical Problems Related to the Patients Medication Intake [Pg.106]

Felodipin tablet Unsuitable for dissolving since a gel is formed that blocks the tube flow Change drug. Another calcium channel blocker [Pg.106]

Omeprazole Each particle in the capsule is protected by an acid stable content that must not be crushed. The granules in the capsule can be too large for tube administration. Change drug. Another proton-pump inhibitor with smaller granules such as Nexium or Prilosec/Losec MUPS. Special instructions are available [Pg.106]


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