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Probe array labeled target oligonucleotides

Figure 1. (a) Recognition of a solution-borne nucleic acid (target) by a nucleic acid probe immobilized on a surface, (b) Fluorescence microscope image of a 1.28 cm X 1.28 cm probe array with 200 pm x 200 pm synthesis sites on which labeled target oligonucleotides have adsorbed. [Pg.207]

Photometer, Fig. 2 DNA microarrays. The probes are complementary fragment oligonucleotides, of target DNA or mRNA spotted onto the microarray surface. This type of array is typically hybridized with target cDNAs that are labeled with fluorophores. The samples are amplified by PCR and hybridized to the microarray and then scanned in... [Pg.2719]

FIGURE 14.1 Scanometric DNA array detection with enlarged nanoparticle probes. Use of oligonucleotide targets, labeled with gold nanoparticles, for recognizing DNA segments on a chip (reproduced from [13] with permission). [Pg.466]


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Oligonucleotide probe arrays

Oligonucleotide probes

Oligonucleotide targeting

Oligonucleotides probe

Probe array

Probes labelling

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