Prisma model polar compounds

The PRISMA model is a structured trial-and-error method that covers solvent combinations for the separation of compounds from low to high polarity. Initial experiments are done with neat solvents, covering the eight groups of the Snyder solvent classification triangle. 

Dallenbach-Tolke, K., Nyiredy, S., Meier, B., Sticher, O. (1986) Optimization of overpressured layer chromatography of polar, naturally occuring compounds by the PRISMA model, J. Chromatogr. A., 365, 63-72. 

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