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Prion structural biology

Keywords Prion diseases Prion protein folding Prion strains Prion structural biology Prions... [Pg.135]

How much is structural biology involved in studying prion systems ... [Pg.358]

R275 R. Cappai, M. F. Jobling, C. J. Barrow and S. Collins, Structural Biology of Prions , Contrib. Microbiol., 2001, 7, 32... [Pg.21]

The PK-resistance of PrPSc is an easily measurable operational parameter that has played a fundamentally important role in the evolution of concepts regarding the nature of mammalian prions. However, from the perspective of structural biology, this parameter is merely a surrogate of structural information, as PK-resistance may be associated with different structural motifs, and may also result from the presence of additional molecules that associate with PrPSc and prevent access of the protease to potential cleavage sites. [Pg.147]

Homemann S, Christen B, von Schroetter C et al (2009) Prion protein library of recombinant constructs for structural biology. EEBS J 276 2359-2367... [Pg.160]

Viles JH, Klewpatinond M, Nadal RC (2008) Copper and the structural biology of the prion protein. Biochem Soc Trans 36 1288-1292... [Pg.161]

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See also in sourсe #XX -- [ Pg.135 ]



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