Principal component analysis Filament

Fig. 26. Global shape classification of filamentous species using Principal Components Analysis...

The myofibrillar proteins make up 50-60% of the total protein of muscle cells. Insoluble at low ionic strengths, these proteins dissolve when the ionic strength exceeds -0.3 and can be extracted with salt solutions. Analysis of isolated mammalian myofibrils86 shows that nine proteins account for 96% or more of the protein myosin, which constitutes the bulk of the thick filaments, accounts for 43% and actin, the principal component of the thin filaments, 22%. 

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