Preparing Aldehydes and Ketones A Review

In previous chapters, we have studied a variety of methods for preparing aldehydes and ketones, which are summarized in Tables 20.1 and 20.2, respectively. 

TABLE 20.1 A SUMMARY OF ALDEHYDE PREPARATION METHODS COVERED IN PREVIOUS CHAPTERS 

When treated with a strong oxidizing agent, primary alcohols are oxidized to carboxylic acids. Formation of an aldehyde requires an oxidizing agent, such as PCC, that will not further oxidize the resulting aldehyde. 

Ozonolysis will cleave a C=C double bond. If either carbon atom bears a hydrogen atom, an aldehyde will be formed. 

Hydroboration-oxidation results in an anti-Markovnikov addition of water across a tt bond, followed by tautomerization of the resulting enol to form an aldehyde. 

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Preparing Aldehydes and Ketones A Review Introduction to Nucleophilic Addition Reactions Oxygen Nucleophiles Nitrogen Nucleophiles Mechanism Strategies Sulfur Nucleophiles Hydrogen Nucleophiles Carbon Nucleophiles Baeyer-Villiger Oxidation of Aldehydes and Ketones Synthesis Strategies... 

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