Prenyl groups Subject

This chapter discusses protein prenylation. The structural diversity of this type of lipidation is discussed, along with the enzymes that attach prenyl groups to proteins. Finally, possible roles of protein prenyl groups in cellular processes are discussed. More detailed reviews on the subject of protein prenylation have been published recently (Glomset et al., 1990 Casey, 1992 Clark, 1992). 

The 2-lerl-prenyl group itself stems from the mevalonate pathway and is introduced in a non-stereospecific manner, as shown by isotope labelling studies [164], The order of oxidations, of Diels-Alder reactions and of the tcrt-prenyl migration is still a subject of research on the individual alkaloids. 

---