Practical guidelines factors

Smith TJ, et al. 2006 Update of Recommendations for the Use of White Blood Cell Growth Factors An Evidence-Based Clinical Practice Guideline, www.asco.org accessed May 17, 2006. 

Practitioner acceptance of a practice guideline is an important determinant of its success and can vary across MCOs, depending on how the guideline was developed and the focus of the guideline. For example, involvement of local expert physicians (vs. unknown physicians from elsewhere) can support use of a practice guideline. Another factor influencing the usefulness of a practice guideline is its brevity and simplicity... 

Ozer, H., J.O. Armitage, C.L. Bennett, J. Crawford, G.D. Demetri, P.A. Pizzo, C.A. Schiffer,T.J. Smith, G. Somlo, J.C. Wade, J.L. Wade, 3rd, R.J. Winn, A.J. Wozniak, and M.R. Somerfield, 2000 update of recommendations for the use of hematopoietic colony-stimulating factors evidence-based, clinical practice guidelines. American Society of Clinical Oncology Growth Factors Expert Panel. J Clin Oncol, 2000.18(20) 3558-85. 

American Society of Clinical Oncology (ASCO) http //www.asco.org Clinical practice guidelines for chemotherapy and radiotherapy protectants, hematopoietic colony-stimulating factors, antiemetics, bisphosphonates in breast cancer, and treatment of selected neoplastic diseases. 

In contrast to good guideline development, the determination of whether guidelines are useful depends upon their readability, computer compatibility, and other factors. Outcomes management takes the results of the outcomes research and incorporates them into clinical practice guidelines to theoretically help ensure all patients receive the most effective treatment available. ... 

Ozer H, Armitage JO, Bennett CL, et al. 2000 update of recommendations for the use of hematopoietic colony-stimulating factors Evidence-based, clinical practice guidelines. J Clin Oncol 2000 18 3558-3585. 

Smith, T.J., Khatcheressian, J., Lyman, G.H., et al. 2006 update of recommendations for the use of white blood cell growth factors an evidence-based clinical practice guideline. J. Clin. Oncol. 24, 3187-3205 (2006)... 

Froa the above discussion it should be obvious that the selection of an appropriate objective function is a difficult task. The choice of the objective function is a critical factor in automated aethods development, since it is used to define the response surface. It is highly likely that different objective functions will result in the production of different response surfaces and the location of different optimum ejqaerimental conditions for the separation. Yet, it is not possible to set hard guidelines for the selection of the objective function, which must be chosen by practical experience keeping the objectives of the separation in mind. 

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