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PPARy agonists, animal models

Thiazolidinediones (PPARy-agonists) Thiazolidine-diones ( pioglitazone, rosiglitazone) lower blood glucose levels in animal models of insulin resistance and also in insulin resistant patients. They are agonists of the peroxisome proliferator-activated receptor y (PPARy). Because they enhance the effect of insulin and reduce serum insulin levels in insulin resistant patients, thiazolidinediones are usually referred to as insulin sensitizers . [Pg.425]

Preclinical Studies of PPARy Agonists in Animal Models of AD. 97... [Pg.81]

Fig. 9.9 Chemical structures of PPARy agonists that have been used for the treatment of AD in animal and cell culture models. RosigUtazone (a) pioglitazone (b) ciglitazone (c) and troglitazone (d)... Fig. 9.9 Chemical structures of PPARy agonists that have been used for the treatment of AD in animal and cell culture models. RosigUtazone (a) pioglitazone (b) ciglitazone (c) and troglitazone (d)...
See other pages where PPARy agonists, animal models is mentioned: [Pg.122]    [Pg.124]    [Pg.190]    [Pg.185]    [Pg.83]    [Pg.91]    [Pg.93]    [Pg.97]    [Pg.98]    [Pg.283]    [Pg.323]    [Pg.85]    [Pg.346]    [Pg.215]    [Pg.244]    [Pg.157]    [Pg.164]    [Pg.90]   
See also in sourсe #XX -- [ Pg.97 ]



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Agonist model

Animal models

Model animal models

PPARy agonists

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