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PPARs receptor

Action on nuclear PPAR receptors has also been proposed but the physiologic role of this interaction has not been determined. [Pg.441]

A small number of 3D-QSAR studies (203, 204) on the thiazolidinediones have been reported, but these agents and the PPAR receptors are not particularly well suited for this type of analysis. 3D-QSAR studies are highly dependent on alignment, which can be difficult with very flexible molecules that bind to a receptor principally by large regional diffuse hydrophobic interactions. [Pg.30]

Corticotropin-releasing factor (CRF) receptor modulators CRF antagonists may act on depression, various other neuropsychiatric disorders and immune diseases. PPARs, an essential group of nuclear receptors PPARa receptors are involved in dyslipemias, atherosclerosis and obesity PPARy receptors are mainly involved in diabetes but also in dyslipemias, hypertension, inflanunation and cancer PPARS receptors, in addition to dyslipemia control, are involved in fertility and cancer. ... [Pg.86]

RXR can form heterodimers with a wide variety of other nuclear-acting receptors, including those for vitamin D (section 11.3.3), thyroid hormone (section 11.15.3-3), long-chain polyunsaturated fatty acids derivatives (the so-called PPAR receptor) and one for which the physiological ligand has not yet been identified (the COUP receptor). [Pg.339]


See other pages where PPARs receptor is mentioned: [Pg.475]    [Pg.93]    [Pg.136]    [Pg.65]    [Pg.943]    [Pg.1005]    [Pg.203]    [Pg.203]    [Pg.57]    [Pg.57]    [Pg.57]    [Pg.30]    [Pg.202]    [Pg.560]    [Pg.298]    [Pg.298]    [Pg.55]    [Pg.255]    [Pg.255]    [Pg.255]    [Pg.249]    [Pg.202]    [Pg.560]    [Pg.30]    [Pg.263]   


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PEROXISOME PROLIFERATED -ACTIVATED RECEPTORS (PPARS)

PPAR

PPAR-y receptor

PPARS

Peroxisome proliferation-activated receptor PPAR)

Peroxisome proliferator activator receptor- (PPAR

Peroxisome proliferator-activated receptor PPAR agonists)

Peroxisome proliferator-activated receptor PPAR)

Peroxisome proliferator-activated receptor PPAR) pathway

Peroxisome proliferator-activated receptor-alpha (PPAR

Peroxisome proliferator-activated receptor-y (PPAR

Peroxisome proliferator-activated receptors PPARs), fatty acid ligands

Peroxisome proliferators activated receptor PPAR)

Peroxisome proliferators activator receptor PPAR) agonists

Peroxisome-proliferator activated receptors PPARs)

Proliferator-activated receptor PPAR)-gamma

Receptor PPAR)

Receptor PPAR)

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