Powder recent inhalation systems

TABLE 7 More Recent Dry Powder Inhalation Systems ... 

Table 7 More recent dry powder inhalation systems ...

Recently, Bustami et al. have investigated the feasibility of the ASES (aerosol solvent extraction system) process to generate microparticles of proteins for inhalation. Protein powders generated were of particle size 100nm-500nm. In vitro performance showed 65, 40, and 20wt.% respirable fraction for lysozyme, albumin, and insulin, respectively. Little or no loss of monomer content was observed for these proteins. 

Dry powder inhalers These are inhalers that typically fall into two general types of commercially available systems single-dose and multidose systems. The multidose systems have been finding increased use in recent years and are generally either passive devices, where the patient provides the energy to disperse the drug powder in a stream of inspired air, or active devices, in which the energy comes from the device. 

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