Powder multidose oral

The structure of this chapter is such that after orientation on the application of oral dosage forms and their definitions, at first the general aspects of formulation and preparation of powder mixtures are dealt with. Specific information about the respective dosage forms are then given in separate sections on capsules and powders (single dose, multidose and cachets). 

Oral powders are preparations consisting of solid, loose, dry particles of varying degrees of fineness. They contain one or more active substances, with or without excipients and, if necessary, colouring matter (...) and flavouring substances. They are generally administered in or with water or another suitable liquid. They are presented as single-dose or multidose preparations [6]. 

Sodium sulfate is an example of multidose powder, which is used as laxative in case of intoxication the patient should take several grams. To make this preparation more patient-friendly, the required quantity of Sodium sulfate decahydrate can be weighed into a dry bottle, which basically makes it a divided powder. Prior to use, the required amount of water is added to dissolve the powder. This may be drme in the pharmacy or elsewhere by the patient or the caregiver. An advantage of a powder over an oral solution is that the preparation has a l(Mig shelf life without the need for a preservative. 

Orally administered medicines require the pharmacist s advice on when (before, with or after the meal) and how (with a full glass of water, no milk, etc.) to take the medicine. When single-dose or multidose powders are dispensed, patients must be taught on the exact technique for measuring the dose to be administered and the proper mode of administration. Should the powder be mixed in a liquid What liquid and volume Can the powder be mixed with food (hot or cold) How long it can be kept after mixing ... 

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