Potassium ruthenate nitriles

Potassium ruthenate, K2RUO4, is prepared in situ from ruthenium trichloride and aqueous persulfate. The reagent catalyzes persulfate oxidations of primary alcohols to acids, secondary to ketones, and primary amines to nitriles or acids at room temperature in high yields [196],... 

More intensive dehydrogenation of primary amines having two hydrogen atoms on the adjacent carbons leads to nitriles. Such dehydrogenations are accomplished by argentic oxide cobalt peroxide [1136], nickel peroxide [936], lead tetraacetate [443, 444], sodium hypochlorite [692], potassium ferricyanide [924], and potassium ruthenate [196] (equation 513). 

Potassium ruthenate (K2RUO4) was used as a catalyst for the oxidation of benzy-lamine with K2S2O8 [109]. Primary amines can be converted to nitriles readily by aerobic oxidation reactions. James and coworkers reported that aerobic oxidative transformation of primary amines to nitriles can be carried out in the presence of a ruthenium porphyrin complex Ru(TMP)(0)2 (1) (100%) (Eq. (7.59)) [110]. 

Aromatic nitriles are now also available in good yields from aryl iodides by reaction with sodium cyanide impregnated on alumina/ from primary aralkyl-amines by oxidation with a potassium ruthenate-potassium persulphate system/ ... 

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See also in sourсe #XX -- [ ]

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