Potassium hydroxyquinoline sulphate

Use. Potassium hydroxyquinoline sulphate is used topically in concentrations of 0.05 to 0.5%. 

It was shown by Hartley and LinnelF that potassium hydroxyquinoline sulphate is almost certainly a simple mixture of potassium sulphate and 8-hydroxyquinoline sulphate. This is substantiated by extraction of the compound with ethanol, when complete separation of the two components results. 

The 4-aminophenazone method (see under Phenol, p. 514) has been applied by Savidge to a cream containing 7-5 per cent of zinc oxide and 0 1 per cent of potassium hydroxyquinoline sulphate. 

The neutral phosphatase of tobacco XD-6 cells [M-Ia] was strongly inhibited by sodium molybdate, and moderately by copper sulphate, zinc sulphate and potassium dihydrogen phosphate (Ninomiya et ah, 1977). The alkaline phosphatase of Lysobacter enzymogenes was relatively insensitive to phosphate and arsenate, but was 97% inhibited by 0.05 mM EDTA and 99% by 0.5 mM 8-hydroxyquinoline (von Tigerstrom and Stelmaschuk, 1986). Yeast phytase [Saccharomyces spp.) was greatly... 

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