Porphyrins recognition

The PBRis distinct from the central BZ receptor although both can be present in the same tissues in differing ratios. PBRs are predominately localized on the outer mitochondrial membrane and are thus intracellular BZ recognition sites. The PBR is composed of three subunits an 18,000 mol wt subunit that binds isoquinoline carboxamide derivatives a 30,000 mol wt subunit that binds BZs and a 32,000 mol wt voltage-dependent anion channel subunit. The porphyrins may be endogenous ligands for the PBR. PBRs are involved in the control of cell proliferation and differentiation and steroidogenesis. 

Multifunctional and chiral porphyrins as model receptors for chiral recognition 98ACR81. 

Porphyrins are very attractive as a platform for the design of sensors for molecule recognition. The flat and relatively rigid structure of porphyrins offers the possibility of constructing various types of recognition sites. Numerous functionalized... 

Seel C, Galdn A, de Mendoza J (1995) Molecular Recognition of Organic Acids and Anions -Receptor Models for Carboxylates, Amino Acids, and Nucleotides. 175 101 -132 Sendhoff N,see KnopsP(1991) 161 1-36 Sessler JL, Burrell AK (1991) Expanded Porphyrins. 161 177-274... 

---