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Porcine glucagon

Deduce the probable conformation of porcine glucagon with the following sequence (construct initial structure in a helix from amino acids with HyperChem which lists residue ID in PDB file) by geometry optimization until the difference in energies between the successive steps is less than 1.0 kcal/mol or rms gradient of 0.1 kcal/(mol-A) ... [Pg.337]

Fig. 3. Plots of the logarithmic capacity factors for hen lysoqnne and several hormonal polyp tides against the volume fraction, p of the organic solvent in water-acetonitrile isocratic mobile phases. Conditions Column, ju-Bondapak Cig flow-rate, 2.0 ml/min primary mobile phases, (a) water - 4 mM sodium sulphate-15 mM orthophosphoric acid, pH 2.2, and (b) water - 4 mM sulphuric add-lS mM orthophosphoric acid-15 mM triethylamine with the acetonitrile content adjusted over the range 0.0-0.8. The polypeptide key is 1 hen lysozyme 2 = porcine glucagon 3 = bovine insulin 4 = bovine insulin fi chain 5 = arginine vasopressin 6 = lysine vasopressin. From [2],... Fig. 3. Plots of the logarithmic capacity factors for hen lysoqnne and several hormonal polyp tides against the volume fraction, p of the organic solvent in water-acetonitrile isocratic mobile phases. Conditions Column, ju-Bondapak Cig flow-rate, 2.0 ml/min primary mobile phases, (a) water - 4 mM sodium sulphate-15 mM orthophosphoric acid, pH 2.2, and (b) water - 4 mM sulphuric add-lS mM orthophosphoric acid-15 mM triethylamine with the acetonitrile content adjusted over the range 0.0-0.8. The polypeptide key is 1 hen lysozyme 2 = porcine glucagon 3 = bovine insulin 4 = bovine insulin fi chain 5 = arginine vasopressin 6 = lysine vasopressin. From [2],...
Extracted porcine C-peptide (21), porcine glucagon (24), porcine monocomponent insulin (25), porcine pancreatic polypeptide (36), porcine proinsulin (30), somatostatin (24), vasoactive intestinal polypeptide (19)... [Pg.530]

Traditionally, glucagon preparations utilized therapeutically are chromatographically purified from bovine or porcine pancreatic tissue. (The structure of bovine, porcine and human glucagon is identical, thus eliminating the possibility of direct immunological complications). Such commercial preparations are generally formulated with lactose and sodium chloride and sold in freeze-dried form. Glucagon, 0.5-1.0 units (approximately 0.5-1.0 mg freeze-dried hormone), is administered to the patient by s.c. or i.m. injection. [Pg.306]

Glucagon Used to reverse insulin-induced h5q)oglycaemia Porcine/bovine pancreatic tissue... [Pg.13]

Glucagon Bovine and porcine pancreata Treatment of acute hypoglycemia... [Pg.210]

Schwyzer and Rittel synthesized Lys(Boc) and employed this derivative for the synthesis of porcine ACTH Wuencsh et al. synthesized glucagon by this procedure. [Pg.620]

A comparison of the sequence of secretin with that of the blood sugar elevating hormone from the pancreas, glucagon [124], reveals extensive homology between the two peptides. Not less than 14 positions are occupied by identical amino acids (in the porcine sequences) ... [Pg.167]

K. Tatemoto, V. Mutt, Isolation and characterization of the intestinal porcine PHI (PHI-27), a new member of the glucagon-secretin family. Proc. Natl. Acad. Sci. USA 78 6603-6607 (1981) K. Tatemoto, V. Mutt, Chemical determination of polypeptide hormones. Proc. Natl. Acad. Sci. USA 75, 4115-4119 (1978)... [Pg.178]

Glucagon 30 amino adds Bovine or porcine pancreas or synthetic Reversal of insulin induced hypoglycaemia... [Pg.555]

See other pages where Porcine glucagon is mentioned: [Pg.109]    [Pg.176]    [Pg.227]    [Pg.186]    [Pg.109]    [Pg.176]    [Pg.227]    [Pg.186]    [Pg.34]    [Pg.209]    [Pg.125]    [Pg.154]    [Pg.45]    [Pg.305]    [Pg.697]    [Pg.1574]    [Pg.1057]    [Pg.143]    [Pg.145]    [Pg.279]    [Pg.390]    [Pg.105]    [Pg.275]    [Pg.253]    [Pg.214]   
See also in sourсe #XX -- [ Pg.530 ]



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