Polyurethane nanoparticles, a new tool for biomedical applications

Morral-Ruizl P. Melgar-Lesmes C. Solans, M.J. Garda-Celma -  

1 University of Barcelona, Barcelona, Spain institute of Advanced Chemistry of Catalonia (IQAC-CSIC) and Networking Research Center on Bioengineering, Biomaterials and Nanomedicine, CIBER-BBN, Barcelona, Spain Corresponding author mjgarcia ub.edu 

Nano-anulsions constitute an attractive alternative for preparing polyurethane nanoparticles because of their small droplet size and, consequently, very large surface area and high kinetic stabiUty. - Nano-emulsions are a class of emulsions with a uniform and extremely small droplet size, usually ranging between 20 and 200 nm. They can be classified as oil-in-water (OAV) or water-in-oil (W/O) nano-emulsions if the internal phase is constituted by oil or aqueous droplets dispersed in aqueous or oily external phase, respectively. Therefore both hydrophobic and hydrophilic 

Nature of nanoparticle Emulsification method Nature of nanoemulsion Monomers Surfactants Polymerization and emulsification parameters Particle size (nm) References 

Polyurethane High-energy (ultrasonication) OAV IPDF1,12-dodecanediol IPDI/bisphenol A IPDI/neopentyl glycol SDS Influence of diol monomer 200nm Tiarks et al.  

---