Nano-emulsions

Anton, N., Benoit, J. P. Saulnier, P. (2008). Design and production of nanopartides formulated from nano-emulsion templates - A review. Journal of Controlled Release, Vol. 128, 3, (June 2008), pp. (185-199), ISSN 0168-3659... 

Use of Nano-emulsions as Templates for the Preparation of Polymeric Nanoparticles 167... 

Izquierdo, P., Esquena, J., Tadros, T.F., Dederen, C., Garcia, M.J., Azemar, N. and Solans, C. (2002) Formation and stability of nano-emulsions prepared using the phase inversion temperature method. Langmuir, 18 (1), 26-30. 

Forgiarini, A., Esquena, J., Gonzalez, C. and Solans, C. (2001) Formation of nano-emulsions by low-energy emulsification methods at constant temperature. Langmuir, 17 (7),... 

Sadurm, N., Solans, C., Azemar, N. and Garci a-Celma, M.J. (2005) Studies on the formation of O/W nano-emulsions, by low-energy emulsification methods, suitable for pharmaceutical aplications. Emulsion polymerization initiation of polymerization in monomer droplets., 26, 438-445. 

Fernandez, P., Andre, V., Rieger, J. and Kuhnle, A. (2004) Nano-emulsion formation by emulsion phase inversion. Colloids and Surfaces A Physicochemical and Engineering Aspects, 251, 53-58. 

Sole, I., Maestro, A., Gonzalez, C., Solans, C. and Gutierrez, J.M. (2006) Optimization of nano-emulsion preparation by low-energy methods in an ionic surfactant system. Langmuir, 22 (20), 8326-8332. 

Bouchemal, K., Briangon, S., Perrier, E. and Fessi, H. (2004) Nano-emulsion formulation using spontaneous emulsification solvent, oil and surfactant optimisation. International Journal of Pharmaceutics, 280, 241-251. 

Chattopadhyay, D.P. andVyas, D.D. (2010) Effect of silicone nano-emulsion softener on physical properties of cotton fabric. Indian Journal of Fibre and Textile Research, 35 (1), 68-71. 

Lesueur, D., Herrero, L., Uguet, N., Hurtado, J., Pena, J.L., Potti, J.J., Walter, J. and Lancaster, I. (2008) Bitumen nano-emulsions and their interest for cold recycling of bituminous mix. Carreteras, 4 (158), 48-53. 

Caldero, G., Garcfa-Celma, M.J. and Solans, C. (2011) Formation of polymeric nano-emulsions by a low-energy method and their use for nanoparticle preparation. Journal of Colloid and Interface Science, 353, 406-411. 

Spemarth, L. and Magdassi, S. (2007) Preparation of ethylcellulose nanoparticles from nano-emulsion obtained hy inversion at constant temperature. Micro el Nano Letters, 2, 90-95. 

P. Izquierdo, J. Esquena, T.F. Tadros, J.C. Dederen, M.J. Garcia, N. Azemar, and C. Solans Formation and Stability of Nano-Emulsions Prepared Using the Phase Inversion Method. Langmuir 18, 26 (2002). 

P. Fernandez, V. Andre, J. Rieger, and A. Ktlhnle Nano-Emulsion Formation by Emulsion Phase Inversion. Colloid and Surfaces A Physicochem. Eng. Aspects 251, 53 (2004). 

Robert J. Bianchini, Colgate-Palmolive Company We just signed an agreement with the University of Michigan to get into antimicrobial nano-emulsions to control anthrax and other diseases. We had a lot of problems getting IP results. In the end, the university did set up a spin-off company. If there is any way that IP issues can be resolved with universities, it certainly would help increase the rate of the innovation process. Our company wanted to protect itself, and we needed the agreement worked out before we could move forward. 

Improved bioavailability. More than 40% of the NCEs (new chemical entity) discovered have good membrane permeability but poor aqueous solubility (i.e.. Biopharmaceutics Classification System II). By formulating the NCE in solution inside a Softgel (e.g., lipid based) or in micro/nano emulsion, the solubility and hence the bioavailability of the compound may be improved. ... 

Thus, droplets prepared close to the PIT will be smaller than those prepared at lower temperatures. These droplets are relatively unstable towards coalescence near the PIT, although by rapid cooling of the emulsion the smaller size can be retained. This procedure may be applied to prepare mini (nano) emulsions. 

Steric Stabilisation and the Role of the Adsorbed Layer Thickness 297 Nano-emulsions 20 80 o/w - Silicone oils... 

Much of the work in this area has been done in emulsions having a droplet size of more than 1 pm, and the application of submicron (nano) emulsions in encapsulation of oils and flavors is relatively new in the literature. Some works have been carried out to determine the influence of submicron emulsions produced by different emulsification methods on encapsulation efficiency and to investigate the encapsulated powder properties after SD for different emulsion droplet sizes and surfactants. The process has been referred to as nanoparticle encapsulation since a core material in nanosize range is encapsulated into a matrix of micron-sized powder particles (Jafari et al., 2008). This area of research is developing. Some patents were filed in the past describing microemulsion formulations applied to flavor protection (Chung et al., 1994 Chmiel et al., 1997) and applications in flavored carbonated beverages (Wolf and Havekotte, 1989). However, there is no clear evidence on how submicron or nanoemulsions can improve the encapsulation efficiency and stability of food flavors and oils into spray-dried powders. 

Izquierdo, R, Feng, J., Esquena, J. et al. 2005. The influence of surfactant mixing ratio on nano emulsion formation by the pit method. J. Colloid Interface Sci. 285 388-394. 

Morales, D., Gutierrez, J.M., Garcia-Celma, M.J., and Solans, Y.C. 2003. A study of the relation between bicontinuous micro emulsions and oil/water nano-emulsion formation. Langmuir 19 7196-7200. Mosca, M., Ceglie, A., and Ambrosone, L. 2008. Antioxidant dispersions in emulsified olive ods. Food Res. Int. 41 201-207. 

Solans, C., Izquierdo, R, NoUa, J., Azemar, N., and Garcia-Celma, M.J. 2005. Nano-emulsions. Curr. Opin. Colloid Interface Sci. 10 102-110. 

Garti, N. Yuli-Amar, I., Micro- and nano-emulsions for delivery of functional food ingredients. In Delivery and Controlled Release of Bioactives in Foods and Nutraceuticals, Garti, N., (Ed.) Woodhead Publishing Limited, Cambridge, U.K., 2008, pp. 149-183. 

Jafari S.M., 2009. Encapsulation of nano-emulsions by spray drying. PhD, Pub LAP Lambert, Saarbriicken, Germany. 

Formation and stability of nano-emulsions prepared using the phase inversion temperature method, Langmuir 18, 26-30 (2002). 

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