Polysiphonia urceolata

Wang S et ai, Chaetopyranin, a benzaldehyde derivative, and other related metabohtes from Chaetomium globosum, an endophytic fungus derived from the marine red Agp Polysiphonia urceolata, J Nat Prod 69 622— 62 y, 2006. 

Chemical investigation of the endophytic fungus Chaetomium globosum, which was isolated from the inner tissue of the Chinese marine red alga Polysiphonia urceolata, resulted in the isolation of chaetopyranin (107), a new benzaldehyde secondary metabolite. Compound 107 displayed moderate radical scavenging activity in the DPPH assay, and also exhibited moderate to weak cytotoxicity toward several tumor cell lines. 

TYR is 4-hydrox3 henylethylamine. TYR occurs in many plants, fungi, and animals but is rare in algae. It was found in brown alga Laminaria saccharina and in red algae Chondrus crispus and Polysiphonia urceolata [16]. 

Li, K., Li, X.-M., Ji, N.-Y, and Wang, B.-G. (2007) Natural bromo-phenols from the marine red alga Polysiphonia urceolata (Rhodomelaceae) structural elucidation and DPPH radicalscavenging activity. Bioorg. Med. Chem., 15, 6627-6631. 

The Ascomycete Chaetomium globosum, an endophyte of Polysiphonia urceolata, contains two new derivatives among a dozen aromatic compounds (including substituted benz-aldehydes and anthraquinones), most of which have already been isolated from terrestrial fungi. Some of these derivatives are moderately antiradical and cytotoxic (Wang et al., 2006). 

---