Polysiloxanes, imprinted

Liquid crystalline imprinted materials have been synthesized (Fig. 24) from polysiloxanes with mesogenic side-chains. In some of them, acetophenone was chosen as template and was covalently linked to the mesomorphous network via a ketal link [ 199]. In the others, the templates (carbobenzoxy-L-phenylala-nine, 1,8-diaminonaphthalene or theophylline) were in interaction with the mesomorphous polymer via hydrogen bonding [200]. All the imprinted networks were obtained as dense membranes. 

With time and improved synthetic protocols, larger templates (fuUerenes, dendrimers, nanoparticles, colloids, micelles, lipid bilayers, self-assembled block copolymers, oligonucleotides, DNA and proteins) have been imprinted [14] and the choice of matrices has expanded to liquid crystal polysiloxanes, carbon networks, zeolites, layered aluminophosphates and colloidal crystals, though organic polymer networks remain the dominant imprint casting medium [14]. 

Glad, M. Norrloew, O. Sellergren, B. Siegbahn, N. Mosbach, K. Use of silane monomers for molecular imprinting and enzyme entrapment in polysiloxane-coated porous... 

Two major types of materials have until now been applied to molecular imprinting, either organic polystyrenes/polyacrylates, or inorganic polysiloxanes. Variations are abundant but these have nevertheless been the most popular, sometimes also used in combination. In this chapter, a survey of building blocks is given and basic synthetic schemes presented. Since organic matrices are by far the more important, organic polymeric systems based on free-radical polymerization of vinyl monomers are exclusively covered. An account on polysiloxane chemistry is covered by Chapter 11 in this volume. 

M. Glad, O. Norrlow, B. Sellergren, N. Siegbahn and K. Mosbach, Use of Silane Monomers for Molecular Imprinting and Enzyme Entrapment in Polysiloxane-Coated Porous Silica, / Chromatogr., 1985, 347(1), 11-23. 

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