Polysaccharide lyases disaccharides

Rye, C. S. Withers, S. G., The synthesis of a novel thio-linked disaccharide of chondroitin as a potential inhibitor of polysaccharide lyases. Carbohydr. Res. 2004, 339, 699-703. 

Polysaccharide lyases have been used to produce A -uronate containing disaccharides (Figure 4, la-lr) and higher oligosaccharides from heparin, heparan sulfate, chondroitin sulfates, dermatan sulfate, hyaluronan, and chemically modified GAGs. ... 

Polysaccharide lyases can be combined with separation methods such as chromatography and electrophoresis for the preparation of glycosaminoglycan oligosaccharides for biological evaluations as well as for disaccharide analysis, oligosaccharide mapping and polysaccharide sequencing. 

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